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Abiraterone 250 mg

Prostate cancer is the most common type of cancer that initiates in the prostate gland cells, which is found only in males. The prostate gland is a tiny walnut-shaped gland that produce seminal fluid that helps in the locomotion and nourishment of the sperms.

CRPC i.e. Castration-resistant prostate cancer, is a developed form of prostate cancer. The cancer is no longer entirely responding to medications that down testosterone, with CRPC. It certainly shows the indications of growth, such as increasing prostate-specific antigen even with low testosterone levels. Among prostate cancer patients, almost 10% to 20% are castration-resistant, and among them, 16 percent of the patients do not show evidence for cancer stretching out at the time of diagnosis of castration resistance.

Abiraterone acetate can help to treat metastatic castration-resistant. Abiraterone acetate tablets advance survival for metastatic castration-resistant prostate cancer (mCRPC) patients before and even after chemotherapy. It has a favorable impact on patients’ health-related aspects of life and anguish.

Abiraterone acetate tablets 250 mg

Abiraterone 250 mg is a medication used for the treatment of prostate cancer. Precisely it is used concurrently with corticosteroids for mCRPC (metastatic castration-resistant prostate cancer) and mCSPC (metastatic high-risk castration sensitive prostate cancer). It is a steroidal compound having antiandrogen activity.

Abiraterone impedes the enzymatic action of steroid 17 alpha-monooxygenase that catalyzes the steroid intermediates 17 alpha-hydroxylation, which is involved in testosterone synthesis. It simply works by avoiding the production of androgen i.e. male hormone, which is certainly done by hindering the CYP17 enzyme. This is how it helps to slow down the advancement of prostate cancer. The price of Abiraterone 250 mg is Rs. 28500/bottle.

Administration of Abiraterone tablets

Dosing may be diverse as per the patient’s condition. This is an oral dosage form medication. It must be taken as directed by the physician. Consume the medication via the mouth on an empty stomach at least two hours after or one hour before a meal. This tablet should be taken once a day. Consuming Abiraterone 250 mg with food can thoroughly increase the amount of this drug in the body and advance the risk of side effects. Do not break, chew or crush the tablet and swallow it as a whole. Do not miss a dose and take medication on time. Do not overdose with the medication.

Side effects of Abiraterone 250 mg

Most of the patients consuming Abiraterone  250mg may experience some common side effects. The side effects of Abiraterone acetate are always predictable based on the onset, duration, and severity of the tablet. These side effects are often reversible and may go away as the therapy progresses. These side effects may be relatively manageable. There are various alternatives to prevent or minimize Abiraterone’s side effects.

Some common side effects are as follows:

• Fluid retention
• Intensified liver enzymes (AST)
• Increased triglycerides

Some less common side effects:

• Discomfort
• Muscle aches
• Joint swelling
• Diarrhea
• Cough
• Urinary tract infection
• Peripheral Edema means swelling of feet and hands
• Hypokalemia
• Increased ALT

Contact the physician immediately if any of the following side effects are experienced

• Chest pain or irregularity in heart rate
• Difficulty in breathing
• Higher Fever and chills
• Dizziness
• Significant headache
• Severe fatigue
• Increase in blood pressure
• Unusual bruising or bleeding
• Yellowing of eyes or skin
• Change in stools

Precautions to be taken while consuming Abiraterone 250 mg

• Tell the doctor about any medications before starting this medication if any medications are going on.
• This medication strictly should not be taken by pregnant women without the proper consultation of a physician. While the ongoing treatment of this drug, getting pregnant or breastfeeding should be avoided.
• The risk of QT prolongation may increase if the patient has certain medical conditions. So consult the doctor.
• Men should use a condom or other birth control method during treatment as excretion of abiraterone acetate in semen is not known. Therefore, proper precautions should be taken.

Erlotinib 150 mg (Erlotinib Tablet)

The pancreas drips enzymes that help in digestion and secretes hormones required to regulate sugar metabolism. Pancreatic cancer initiates in the pancreatic tissues, but the most predominant type of pancreatic cancer begins in the cell linings of the duct carrying digestive enzymes. Lung Cancer begins at any part of the lungs. There are two major types of lung cancer: small cell lung cancer and non-small cell lung cancer that usually includes causes such as exposure to particular toxins, smoking, and ancestry history. Pancreatic metastases appear in the near end-stage of small cell lung cancer. Though it is rare, the major hazards of these lesions are obstructive jaundice and acute pancreatitis. For treating this pancreatic and lung cancer, Erlotinib 150 mg is used.

The Erlotinib 150 mg is helpful and safe for non-smoker patients to treat advanced Adenocarcinoma.

Erlotinib 150 mg is a specific tyrosine kinase inhibitor specified for Non-Small Cell lung cancer (NSCLC) and Pancreatic cancer medication. Erlotinib contains erlotinib hydrochloride, and it is a film-coated tablet. It is prescribed for the first-line therapy of sufferers with locally progressive or metastatic NSCLC (Non-Small Cell lung cancer) with EGFR (Epidermal Growth Factor Receptor) triggering mutations or for the patients with stable ailment after first-line chemotherapy. The Erlotinib price in India.

Victims with locally developed and metastatic non-small lung cancer can take this drug with a combination of gemcitabine as a first-time therapy but only as per the proper prescription.

Usage and Dosage of Erlotinib 150 mg

Erlonat 150 mg or Erlotinib 150 mg is an oral dosage form, it must be consumed by the mouth because it is aimed at having a systematic effect, circulating to the various parts of the body through the bloodstream.

For better effects, it is suggested to be taken at the same time every day, and it can be taken with or without food. Do not try to crush or halve the tablet before swallowing nor chew it swallow it as a whole. Take the medication as directed by the doctor.

Medication should be kept going until the ailment advancement, or incompatible toxicity occurs.

Side effects of Erlotinib tablets

Dry skin, joint and muscle pain, dry eyes or irritation in the eyes or redness, diarrhea (sometimes severe conditions) may occur.

Just keep in mind that your doctor has prescribed this medication by judging the benefits greater than the risk factor of side effects. Several patients dealing with this medication usually do not have severe side effects.

Serious side effects of Erlotinib tablets

Some of the serious side effects of the Erlocip 150 mg includes the following:

• Kidney or Renal problems- change in volume of urine.
• Signs of liver disease include nausea, loss of appetite, yellowing of skin/urine/eyes, vomiting, and stomach ache.
• Shortness of breath
• Chest or left arm pain
• Weakness
• Seizures
• Signs of dehydration include dizziness, muscle cramps, etc.
• Black stools, easy bleeding, eye pain, optical changes.

Precautions while using Erlotinib tablets

• Pregnant women should avoid Erlotinib 150 mg, and this drug is not suggested while they are breastfeeding.
• Before consuming this drug, be sure you are not having any liver or kidney problems, eyes, stomach bleeding, or any lung or breathing issue.
• If the patient is often smoking cigarettes, they are advised to stop smoking as smoking cigarettes shows reduced drug exposure.
• This Erlotinib 150 mg should not be used in combination with platinum-based chemotherapy.
• Patients are advised to quickly contact their doctor if any signs or symptoms such as redness in the eye, light sensitivity, eye pain, blurred vision, or visual changes are noticed.

As Erlotinib 150 mg comes with certain usefulness and side effects, it should never be used without consulting a doctor or pharmacist.

Abiraterone acetate, also known as abiraterone 250 mg, is an oral drug for adult male patients with prostate cancer. It is a type of hormone therapy and is used along with prednisone or prednisolone. The abiraterone acetate 250 mg tablets are taken to create an interference with the growth of androgen or testosterone hormones, blocking them in the area of the tumor, adrenal gland, and testes. The enzyme needed for the production of androgen is also blocked with the help of abiraterone acetate. Since this medicine is not an over-the-counter medicine, the individual showing symptoms of such a disease should consult the doctor immediately and get the right prescription. Moreover, the drug is strictly for adult male patients, and not children or adolescent patients. Moreover, if the male patient takes part in any sexual activity, they should take birth control measures to avoid pregnancy as the dust of the medicine that can enter through the skin can harm the unborn child. The abiraterone acetate 250 mg is given to the patients when

– Chemotherapy does not seem to have any effect on the individual and is not needed at the current stage, that is, the beginning stages.

Administration of the abiraterone acetate 250 mg:

The tablets should be taken orally as directed by the physician. It should be taken on an empty stomach, at least an hour before the meals or two hours after. Do not crush or chew on the tablet, rather swallow it whole with the help of water. Taking medicine with food can increase the effects of the medicine on the body and risk health. Moreover, the individual should not discontinue the drug or take more than what has been prescribed. This can lead to overdosing and even cause death.

When should the abiraterone acetate 250 mg be avoided or taken cautiously?

– If the patient has a medical history of diabetes or takes medicines for diabetes.

– If the patient is suffering from or has a medical history of liver problems.

– If the patient is suffering from or has a medical history of heart diseases.

– If the patient has a medical history of high blood pressure or is currently suffering from the illness.

– Consult the doctor if the patient is also taking medicines to treat seizures because of epilepsy.

– Some inactive elements present in the medicine can cause allergy in the patient. So it is advised to discuss the allergies with the physician as well.

– The patient should make it clear before taking this drug if they are on any herbal medicines like st John’s wort and all.

Most common side effects of abiraterone acetate 250 mg:

– Headache

– High blood pressure

– Joint pain

– Common cold

– Bone fractures as well as painful feet and legs

– Increased and painful urination. There may also be a little bleeding.

– Diarrhea

– Breathlessness as well as chest pain.

– Fatigue.

Although this is not the complete list of side effects, these are the most common ones. None of the effects are too serious and should stop after a few weeks of taking medicine. If you experience any abiraterone acetate 250 mg side effects, go to the doctor and consult what to do further. If there are any allergic reactions after taking medicine, the person should also visit the doctor. With this medicine, cancer will not be completely cured, but it prolongs the lifeline by stopping the growth of the cancer cells.

Veenat 400 (Imatinib) is a tyrosine kinase inhibitor and finds immense use in treating various types of blood cancer (like chronic myeloid leukemia and acute lymphocytic leukemia) and gastrointestinal stromal tumors.

It is to be taken for the entire duration that has been advised by the medical practitioner, which will depend on the degree of responsiveness of the patient’s body towards the drug. It’s advisable to administer the medicine at the same time every day, and it should be administered along with food. An incorrect administration of the drug might cause harmful effects. It might take days or even months for any noticeable change to occur, but the medication is not to be stopped unless and until the doctor advises it.

Common allergic reactions to this drug are:

• Nausea
• Muscle Cramps
• Edema
• Musculoskeletal Pain
• Fatigue
• Vomiting
• Rash
• Abdominal Pain
• Diarrhea

The practitioner may advise monitoring of the patient’s liver functions and blood cells. Any unexpected weight gain must be reported to the concerned doctor. The patient is also advised against driving and doing other activities that require mental focus on the part of the doer if they experience a blurry vision with accompanying dizziness, which is normal.

Physicians should positively check the compatibility of this drug with any other medications that the patient would be undergoing simultaneously to prevent any unhealthy interactions between the two and the ensuing irritation.

Benefits of Veenat 400 (Imatinib)

• In Blood Cancer (Chronic Myeloid Leukemia), cancer in the blood-forming tissues decreases the body’s infection-fighting abilities. This drug helps by killing or retarding the multiplication of the cancerous cells. This is a very potent drug, and the patient is advised to avoid alcohol consumption and stay hydrated during the medication.
• In the case of Acute Lymphocytic Leukemia, another form of blood cancer, this medication is quite effective.
• In the case of Gastrointestinal Stromal Tumor (GIST), Veenat 400 (Imatinib) cures by killing the cancerous cells and stopping the growth of tumors in the Interstitial Cells of Cajal (ICC).

Side Effects of Veenat 400 (Imatinib)

Common side-effects of the drug are Edema (Swelling), Nausea, Muscle Cramp, Musculoskeletal (bone, muscle, or joint) pain, Diarrhea, Rash, Fatigue, and Abdominal Pain. The patient may develop one or more of these side effects at the onset of the medication, but it generally goes away once their body adapts to the medication. However, the patient is advised to consult their medical practitioner if the symptoms persist or exacerbate.

Mode and Way of Administration

The drug is to be administered strictly following the dosage prescribed by the practitioner. The tablet is to be swallowed as a whole. The patient is advised against chewing, crushing, or breaking the tablet. It’s advisable to take the drug with food. If the patient accidentally misses a particular drug dose, they are advised to skip it altogether and stick to the normal schedule. There’s no need to double the next dose.

Working of Veenat 400 (Imatinib)

Veenat 400 (Imatinib) is a cancer-curing drug that induces apoptosis (planned cell death) in the bcr-abl positive cells (cancer cells). Bcr-abl tyrosine kinase is a protein-secreting enzyme that causes cancer cells to proliferate abnormally.

Interaction With Other Drugs

The practitioner is advised to check for possible interactions that this drug may have with any other drugs that the patient would be taking. Some of the drugs which can cause serious side effects if they interact with Veenat 400 (Imatinib) are Atorvastatin, Carbamazepine, Fluvastatin, and Lovastatin.