{"id":29299,"date":"2025-09-03T17:20:12","date_gmt":"2025-09-03T11:50:12","guid":{"rendered":"https:\/\/gandhimedicos.in\/?p=29299"},"modified":"2025-09-03T17:20:12","modified_gmt":"2025-09-03T11:50:12","slug":"myeloma-and-the-link-to-ocular-manifestations","status":"publish","type":"post","link":"https:\/\/api.gandhimedicos.in\/?p=29299","title":{"rendered":"Myeloma and the Link to Ocular Manifestations"},"content":{"rendered":"
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The eye dysfunctions may be caused due to several diseases or as a side effect of various treatments. Blurring of vision or other eye defects can be an early sign or symptom of myeloma.<\/p>\n

What is Myeloma?<\/h2>\n

Myeloma is a blood cancer that affects white blood cells, which help the body fight back against the cancer. It is a type of plasma cell cancer. The abnormal plasma cells produce excess antibodies that lose their function to fight cancer cells, and damage other organs like the kidney, liver, etc.<\/p>\n

How Does Myeloma Affect the Eyes?<\/h3>\n

Plasma Cell Infiltration\u2014<\/strong><\/p>\n

The plasma cells directly infiltrate into the orbit (eye socket) or the other eye tissues. It leads to various issues like \u2013<\/p>\n

    \n
  • \u2022\u00a0Bulge in the eyes,<\/li>\n
  • \u2022\u00a0Double vision,<\/li>\n
  • \u2022\u00a0Pain, swelling in the eyes, and the eyelid.<\/li>\n<\/ul>\n

    Increased Thickness of the Blood (Hyperviscosity)<\/strong><\/p>\n

    The excessive amount of plasma cells in the blood causes thickening of the blood, slows down blood flow to the retina, and forms blood clots in the eye, leading to \u2013<\/p>\n

      \n
    • \u2022\u00a0Blurred vision<\/li>\n
    • \u2022\u00a0Bleeding in the eye (retinal hemorrhage)<\/li>\n
    • \u2022\u00a0Double vision<\/li>\n
    • \u2022\u00a0Difficulty to focus<\/li>\n
    • \u2022\u00a0Retinal detachment<\/li>\n
    • \u2022\u00a0Formation of blind spots<\/li>\n<\/ul>\n

      Crystalline Deposits<\/strong><\/p>\n

      The abnormal paraproteins produced by excess secretion of immunoglobulin build up around the eyes, leading to crystalline deposits in the cornea or other structures.
      \nIt causes pain, bulging of the eyes, and double vision.<\/p>\n

      Optic Nerve Compression<\/strong><\/p>\n

      It is the plasma cell tumor or lesion in the orbital bone that exerts pressure on the optic nerve, leading to vision loss, eye pain, and double vision.<\/p>\n

      POEMS Syndrome<\/strong><\/p>\n

      It is a rare condition that occurs due to a blood disorder. It causes the optic nerve to damage and swell, leading to vision loss and dysfunction.<\/p>\n

      Increased Risk of Infections<\/strong><\/p>\n

      Myeloma is a cancer of the immune cells. Reduction in the body’s immunity increases the vulnerability to infections like shingles, herpes, etc., and other eye infections.<\/p>\n

      Myeloma Causes Eye Symptoms as –<\/strong><\/p>\n

        \n
      • \u2022\u00a0Changes in the vision<\/li>\n
      • \u2022\u00a0Dry eyes<\/li>\n
      • \u2022\u00a0Redness in the eye<\/li>\n
      • \u2022\u00a0Irritation in the eye<\/li>\n
      • \u2022\u00a0Photosensitivity<\/li>\n
      • \u2022\u00a0Easy bruising<\/li>\n
      • \u2022\u00a0Watery eyes<\/li>\n
      • \u2022\u00a0Unusual discharge<\/li>\n<\/ul>\n

        Ocular Side Effects From Myeloma Treatment?<\/h3>\n

        The myeloma treatment, involving the high-dose corticosteroids and other chemotherapy drugs, causes ocular side-effects like retinal hemorrhage, conjunctivitis, and cataracts, etc.<\/p>\n

        \u2022\u00a0Corneal Damage\u2013<\/strong> It is the use of corticosteroids that causes a lesion of the epithelial layer of the cornea, or damages the cornea, leading to gritty or sore eyes.<\/p>\n

        \u2022\u00a0Dry Eyes \u2013<\/strong> The stem cell transplantation or chemotherapy suppresses tear formation by damaging or inhibiting the lacrimal glands, or the neuropathy (nerve damage) reduces eye movement and leads to dryness and irritation in the eye.<\/p>\n

        \u2022\u00a0Cataracts:<\/strong> long-term use of steroids causes changes in the structure of the lens, clumping together lens protein, leading to the formation of patches.<\/p>\n

        \u2022\u00a0Glaucoma:<\/strong> The corticosteroid or other immunomodulatory drugs reduce the ability to drain intraocular fluid, causing fluid retention and increasing intraocular pressure. Excessive pressure may cause optic nerve damage, leading to peripheral vision loss.<\/p>\n

        \u2022\u00a0Eye Infections:<\/strong> The myeloma and its treatment reduce immunity, increasing the risk of eye infections like conjunctivitis, etc.<\/p>\n

        \u2022\u00a0Other Health Conditions \u2013<\/strong> various conditions like diabetes, high blood pressure, and thyroid disease increase the risk of eye dysfunction in myeloma patients.<\/p>\n

        Key Takeaways \u2013<\/h3>\n

        Myeloma or its treatment commonly affects the eyes. The regular screening and early detection of ocular symptoms help take timely measures to prevent eyesight loss and improve quality of life.<\/p>\n

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        Gandhi Medicos is at the forefront of cancer care and anticancer drug distribution. It is the trusted anticancer drug exporter to countries worldwide, offering global standard care and premium quality products.<\/p>\n

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          The eye dysfunctions may be caused due to several diseases or as a side effect of various treatments. Blurring of vision or other eye defects can be an early sign or symptom of myeloma. What is Myeloma? Myeloma is a blood cancer that affects white blood cells, which help the body fight back against the […]<\/p>\n","protected":false},"author":1,"featured_media":29307,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-29299","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"\nMyeloma Ocular Manifestations, Ocular Symptoms of Multiple Myeloma - Gandhi Medicos<\/title>\n<meta name=\"description\" content=\"Explore ocular manifestations of multiple myeloma, including vision changes, eye pain, and retinal issues. 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